Arthritis
Arthritis, particularly affecting the hands and knees, is a common complication of advanced hemochromatosis. The excess iron deposited in the joint tissues leads to inflammation and pain, gradually causing joint damage and stiffness. This can significantly impair an individual’s ability to perform daily activities and diminish their quality of life.
The iron-induced joint damage is not reversible, but treatment can help slow the progression and alleviate some symptoms. Regular exercise, weight management, and certain medications can relieve pain and improve joint function, making arthritis management a critical aspect of hemochromatosis care.
Liver Disease or Cirrhosis
The liver is particularly vulnerable to damage from iron overload, with conditions ranging from mild liver disease to cirrhosis, which is characterized by permanent scarring of the liver tissue. Symptoms of liver damage may include fatigue, weakness, and abdominal pain. As the liver function deteriorates, it can lead to more severe health issues, including liver failure.
Regular monitoring and treatment of iron levels can prevent liver disease progression in individuals with hemochromatosis. Lifestyle changes, such as avoiding alcohol and maintaining a healthy weight, can also help protect the liver from further damage. [4]
