Daytime Sleepiness
Intended for evening use, melatonin can induce unwanted drowsiness if taken at other times, though this aligns with its primary function as a sleep aid. However, individuals with diminished melatonin clearance, seen in older adults and infants, might experience prolonged effects, raising questions about morning-after levels. Despite these considerations, studies have shown that melatonin, even when administered during the day, doesn’t impair focus or cognitive performance, challenging the notion of its negative daytime impact. [3]
Research contrasting melatonin with placebo in terms of reaction time and cognitive abilities reveals no significant difference, offering reassurance about its safety during daylight hours.
Drug Interactions and Other Effects
Concerns extend to melatonin’s interaction with other medications, particularly sleep aids like zolpidem, which may amplify negative effects on memory and muscle function. Additionally, melatonin’s influence on body temperature and blood coagulation suggests caution for individuals with specific health considerations. The slight decrease in body temperature and potential blood-thinning effects highlight the importance of consulting healthcare providers before combining melatonin with medications like warfarin.
A study exploring the combined use of melatonin and zolpidem underscores the complexity of drug interactions, urging a thorough review of potential side effects. [4]
